AnavarAnavar (Oxandrolone) was first introduced in 1964 in America and quickly rose as one of the most well-known and popular oral steroids currently in use. Oxandrolone is a DHT based steroid which has had it’s molecular structure somewhat altered which turned it into a C17 Alpha Alkylated oral with heightened anabolic activity. Oxandrolone is a very weak androgen however it possesses a very high anabolic/androgenic ratio.
Oxandrolone is one of the few anabolic steroids which doesn't cause premature growth plate closure, as a result its medical application is for the treatment of osteoporosis and to stimulate development in children. Oxandrolone generally does not cause virilization (secondary sexual male characteristics) in women when used in relatively small doses. (In women this translates to less than 20 mg per day.
Bodybuilder, power lifters, weightlifters and MMA fighters love Anavar Oxandrolone as it creates great increases in strength with minimal water retention. This particular trait is of benefit to speed and strength athletes as it allows them to stay close to their respective weight class. Strength increase comes partially from increased synthesis of phosphocreatine and partially from increases in myofibril numbers without any additional water volume. This effect is of particular benefit for weight classed athletes as it allows increased performance with little corresponding weight gain.
Anavar is also known to greatly increase nitrogen retention as well as inhibiting SHBG (Sex Hormone Binding Globulin) This innate inhibitory effect leads to an overall increase in free testosterone as well as promoting an “unbound state” of all other anabolics within a person’s system.
Because of Anavar’s low androgenic properties it is my opinion that it could/should be used with other more androgenic anabolic steroids. Although Oxandrolone doesn't aromatize at any dose, the addition of the anti-estrogen will cause even greater muscularity and hardness. Oxandrolone is also known for decreasing appetites which makes it an ideal choice for ketogenic diets, low carb diets and pre contest prep. Of further interest to athletes, is that Anavar has been shown to influence lipolysis to a greater extent than most other anabolic steroids. It binds to androgen receptors, it reduces Thyroid Binding Globulin, it increases the utilization of the T3 hormone and it increases red blood cell production which has a direct effect on whole body oxygenation.
Oxandrolone may decrease endogenous testosterone production with moderate doses of up to 50 mg, HOWEVER, doses of greater then 60 mg per day can have a profound suppressive effect on the leydig cells in the Testes and research has shown that the decrease of the aforementioned testosterone level can reach 67%. As a side note the suppressive effects are absent on both sperm count and volume.
Oxandrolone may have a masculinizing effect on female athletes at the doses of approximately 30 milligrams per day and women 5 to 50 mg per day.
Some preferred combinations with Oxandrolone include Halotestin which causes additional increase in strength, definition and hardness, clenbuterol, which causes additional muscularity, Parabolon, in which causes additional strength muscularity and hardness, as well as Winstrol, well known for increases in overall muscularity. If Oxandrolone is to be used in a "stacking cycle" with other highly aromatizing steroids, an anti-estrogen should be added.
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